Bentrio
Drug-free protection

Breathe freely all year.

Drug-free nasal spray for pollen: how does a barrier protect against allergens?

Bentrio is a drug-free barrier nasal spray. It lays a thin gel film of natural bentonite across the nasal lining that traps pollen, dust mites and pet dander before they reach the immune system. Protection works immediately and lasts up to four hours. No drugs, no preservatives, suitable from age six and during pregnancy.

Bentrio forms an invisible barrier inside your nose that traps airborne allergens before they reach you – so pollen, dust mites, and pet dander don't get the last word.

4h
Protection per dose
Zero
Drugs & preservatives
6+
Suitable from age six
Bentrio nasal spray bottle

Works on contact

No drowsiness, no waiting

Developed in Switzerland
Class IIa medical device
Prescription free
Safe in pregnancy and breastfeeding
No drowsiness
Natural bentonite
No preservatives
Up to 4h protection

Act before the first sneeze.

What makes Bentrio different from other allergy products?

Bentrio works one step earlier than most allergy products, which wait for symptoms and then dull them. Bentrio forms its barrier the moment you spray, so allergens are stopped before they ever set symptoms in motion. And if symptoms have already started, that same barrier helps calm and relieve the nose by shielding it from further irritation.

Fast

Starts working immediately on contact – no waiting, no drowsiness, no build-up period.

Powerful

Triple action that shields the nasal mucosa, traps inhaled particles and humidifies.

Free

No drugs, no preservatives – formulated with natural bentonite, a mineral found in nature.

A woman breathing calmly outdoors among spring blossoms

Invisible nasal shield

Active within seconds of a single spray

Naturally derived

From reacting to symptoms, to blocking them at the door.

Why prevent allergens instead of treating symptoms?

Bentrio prevents contact with allergens instead of quieting a reaction that has already started. It lays down a thin, protective film across the nasal lining that intercepts inhaled allergens before the body ever responds.

Think of Bentrio like sunscreen for the nose: a proactive shield you reach for first, not the rescue you reach for last.

Proactive, not reactive

Protects before exposure rather than chasing symptoms.

First-line friendly

A barrier approach suited to mild and moderate allergy sufferers.

Pairs with your routine

Use alone or alongside your existing allergy medication.

Everyday control

Each spray protects for around four hours – simply reapply to stay covered all day outside.

A spray that becomes a shield.

How does Bentrio work inside the nose?

Bentrio is a barrier nasal spray: it lays a gel film of natural bentonite across the nasal lining that traps allergens before the immune system reacts. Unlike antihistamines or corticosteroids, it works purely physically, with no pharmacological active ingredient.

Bentrio is a unique nasal spray gel with clinical proof of efficacy in protecting against allergens such as grass pollen and house dust mites. It provides physical protection – without the typical side effects associated with drug-based solutions.

Bentrio transitions from a spray gel to a liquid for easy, comfortable application, then creates a protective gel barrier on the nasal lining that effectively shields against allergens.

Mode of action

01

Spray gel

In the bottle, Bentrio is a thixotropic gel. A few firm shakes turn it into a sprayable liquid.

02

Becomes liquid

On release it transitions to a fine liquid mist, ensuring an easy and comfortable nasal application.

03

Forms a barrier

Inside the nose it sets into a protective gel film across the lining, shielding against allergens.

One spray. Three ways it protects.

What does bentonite do in a nasal spray?

Bentrio is formulated with bentonite – a naturally occurring mineral with an exceptional ability to absorb and hold particles.

01

Shields

Bentrio forms a thin physical barrier across the nasal mucosa, blocking contact between allergens and the immune system.

02

Traps

The natural bentonite in Bentrio captures inhaled particles – pollen, dust mites and pet dander – and holds them at the surface.

03

Humidifies

Bentrio moisturises the nasal lining and supports its natural defences, leaving a gentle vanilla scent behind.

Clinical evidence

What do the clinical data on Bentrio show?

In the randomised NASAR trial, participants applied either Bentrio or a saline solution three times daily for two weeks. Bentrio significantly reduced the mean daily reflective total nasal symptom score (rTNSS) compared with saline (p = 0.013) and improved disease-related quality of life (RQLQ) highly significantly (p < 0.001). Safety and tolerability were comparable to the saline control.

Set it up once, then it takes seconds.

How do you use Bentrio correctly?

Bentrio is for adults and children from age six. It works right away and keeps going for up to four hours – top up whenever you need to.

Watch how it works

First use only

Getting the pump ready

  1. 1

    Press and hold the pump, then give the bottle a good shake up and down – five times does it.

  2. 2

    Let go, then press again every couple of seconds towards a tissue until the spray comes out evenly. Nothing yet? Just start over.

Every time

Using Bentrio

  1. 1

    Tilt your head forward a little, hold the bottle upright and pop the tip just inside one nostril. Breathe in gently and press once – no sniffing right after.

  2. 2

    Same again on the other side, then wipe the tip and click the cap back on. The gel spreads out on its own to where it is needed most.

Use Bentrio on its own or alongside your other allergy medication. Using another nasal spray too? Take that one first and give it a few minutes before Bentrio.

Comparison

How does a barrier spray differ from other allergy treatments?

Bentrio belongs to the barrier category, which works physically rather than pharmacologically. That is exactly where the differences come from: protection from the first spray, no active ingredients, no systemic effect – and suitable for children from age six as well as during pregnancy and breastfeeding. The table compares the categories, not individual brands.

How does a barrier spray differ from other allergy treatments?
CriterionBarrier spray (Bentrio)Oral antihistamineCorticosteroid nasal spraySaline solution
Mode of actionphysicalpharmacologicalpharmacologicalphysical
Onset of actionon contactapprox. 30–60 minutesdays to full effectimmediate
Active ingredientsnoneyesyesnone
Systemic effectnoneyeslownone
Drowsiness possiblenopossiblerareno
In pregnancy and breastfeedingsuitableask a doctorask a doctorsuitable
Preservativesnoneoftenvaries
Dosingas needed, up to 8× dailyfixed daily dosecontinuous daily therapyas needed
Protection per applicationup to 4 hours, repeatableapprox. 24 hourswith regular useshort
Suitable fromage 6variesvariesvaries
Prescription requirednosometimessometimesno

These entries describe each product category; individual products may differ. Corticosteroid nasal sprays act mainly locally and are absorbed systemically only to a small degree. Bentrio is not a replacement for treatment prescribed by a doctor – do not stop prescribed medication without medical advice.

Made for clean sport.

Can athletes use Bentrio without breaking anti-doping rules?

Bentrio protects through a purely physical gel barrier – no drugs, steroids or antihistamines, and no systemic effect on the body. That makes it suitable for competitive athletes who need clear airways without compromising clean-sport rules.

  • Drug-free mode of action

    A mechanical barrier that traps allergens on contact, with no pharmacological effect on the body.

  • Tested for banned substances

    Screened for drugs and substances on anti-doping lists, so it fits within clean-sport requirements.

  • Chosen by competitive athletes

    Used in training and competition by athletes who cannot risk their airways or their eligibility.

A competitive athlete breathing freely during outdoor training
From daily use

What do users report about Bentrio?

My son suffers badly from hay fever. Since switching to Bentrio, the cortisone spray stays in the drawer – he's protected without any medication at all.
CC.H.Parent
Normally I'd sneeze constantly outdoors this time of year. After my daily walk with Bentrio, I had no reaction for the rest of the day – just a pleasant vanilla scent.
AA.H.Daily walker
Even on allergy tablets the early blossom was rough. A colleague recommended Bentrio and it's been transformative – my runny nose has noticeably calmed despite high pollen.
MM.W.Verified user
Years of allergies and sinusitis, and I'd tried everything. With Bentrio I finally reduced the irritation of my mucous membranes. The effect is genuinely noticeable.
DDr. A.Physician

Superior in the ways that matter.

Who is Bentrio suitable for – and who should avoid it?

No drugs, no preservatives

Bentrio is formulated with natural bentonite. No pharmacological, immunological or metabolic effects.

Protection for up to 4 hours

Bentrio is clinically shown to shield against airborne pollen for hours per application.

Suitable in pregnancy

Bentrio is gentle enough for use during pregnancy and breastfeeding, and from age six.

Developed in Switzerland

Bentrio is designed in Switzerland and manufactured to the highest standards in Europe.

Certified Class IIa (MDR)

Certified under EU MDR 2017/745 (CE 2797) – clinically tested and well tolerated.

Prescription free

Bentrio is available without a prescription, with a well-established safety profile.

Bentrio should not be used if you are hypersensitive to any of its ingredients, or if you have open wounds or an injury inside the nose. If you are unsure whether Bentrio suits you, ask your doctor or pharmacist.

Inside production · NextPharma, Germany

Quality you can see being made.

Where is Bentrio manufactured?

Bentrio is engineered in Switzerland and manufactured at NextPharma in Germany – one of Europe's most respected pharmaceutical producers. Watch how every bottle is filled and checked under exacting standards.

Made in Germany

Produced at our manufacturing partner NextPharma, a trusted European pharmaceutical specialist.

GMP-certified production

Every batch is filled under strict Good Manufacturing Practice and pharmaceutical-grade quality control.

Built to medical standards

Manufactured as a certified Class IIa medical device, traceable from raw material to finished bottle.

Questions, answered.

What do people ask most about Bentrio?

Everything you might want to know before your first spray. Still curious? Reach out and we'll happily help.

Get in touch

Questions about Bentrio? We're here to help.

Talk to our AI assistant for instant answers, or reach the team directly. For partnership and licensing enquiries, our business development team is ready to connect.

Altamira Medica AG

Peter Merian-Strasse 90, 4052 Basel, Switzerland

www.altamiramedica.com

Email us

service@bentrio.com

Send email

Call us

+41 79 969 96 60

Call now